Publications

KC, S., Nguyen, K., Nicholson, V., Walgren, A., Trent, Tony., Gollub, E., Romero, S., Holehouse, A.S., Sukenik, S., Boothby, T.C., Disordered proteins interact with the chemical environment to tune their protective function during drying. bioRxiv (2024).

 

Sanchez-Martinez S, Nguyen K, Biswas S, Nicholson V, Romanyuk AV, Ramirez J, Kc S, Akter A, Childs C, Meese EK, Usher ET, Ginell GM, Yu F, Gollub E, Malferrari M, Francia F, Venturoli G, Martin EW, Caporaletti F, Giubertoni G, Woutersen S, Sukenik S, Woolfson DN, Holehouse AS, Boothby TC. Labile assembly of a tardigrade protein induces biostasis. Protein Science (2024). 10.1002/pro.4941

 

Kumara, U.V.G.S.S., Ramirez, J.F., Boothby, T. The effect of sucrose polymer-size on glass transition temperature, glass former fragility, and water retention during drying. Frontiers in Materials (2024). 11, 1351671

 

Ramirez, J.F., Kumara, U.V.G.S.S., Arulsamy, N., Boothby, T. Water content, transition temperature and fragility influence protection and anhydrobiotic capacity. BBA Advances (2024). 5, 100115

 

Biswas, S., Gollub, E., Yu, f., Ginell, G., Holehouse, A., Sukenik, S., Boothby, T. Helicity of a tardigrade disordered protein contributes to its protective function during desiccation. Protein Science (2024). 10.1002/pro.4872

 

Cesari, M., Boschetti, C., Boothby, T. Physiology of invertebrate sensing in extreme conditions and hostile environment. Frontiers in Physiology (2023). 14, 1334716

 

Sanchez-Martinez, S., Ramirez, J.F., Meese, E.K. et al. The tardigrade protein CAHS D interacts with, but does not retain, water in hydrated and desiccated systems. Scientific Reports (2023). 13, 10449

 

Packebush, M.H., Sanchez-Martinez, S., Biswas, S. et al. Natural and engineered mediators of desiccation tolerance stabilize Human Blood Clotting Factor VIII in a dry state. Scientific Reports (2023). 13, 4542

 

Holmberg J, Henry S, Burnouf T, Devine D, Marschner S, Boothby TC, et al. National Blood Foundation 2021 Research and Development summit: Discovery, innovation, and challenges in advancing blood and biotherapies. Transfusion (2022). 62(11), 2391-2404


Giovannini I, Boothby TC, Cesari M, Goldstein B, Guidetti R, Rebechhi L, Production of reactive oxygen species and involvement of bioprotectants during anhydrbiosis in the tardigrade Paramacrobiotus spatialis. Scientific reports (2022). 12(1), 1-12


Nguyen K, Kc S, Gonzalez T, Tapia H, Boothby TC, Trehalose and tardigrade CAHS proteins work synergistically to promote desiccation tolerance. Communications biology (2022). 5(1), 1-12.


Boothby TC, Water content influences the vitrified properties of CAHS proteins. Molecular Cell (2021). 81(3), 411-413.


Hesgrove, C, & Boothby TC, The biology of tardigrade disordered proteins in extreme stress tolerance. Cell Communication And Signaling (2020). 18(1).


Ren Q, Brenner R, Boothby TC, Zhang Z, Membrane and lipid metabolism plays an important role in desiccation resistance in the yeast Saccharomyces cerevisiae. BMC Microbiology (2020). (1), 1-1322020


Boothby, TC, Mechanisms and evolution of resistance to environmental extremes in animals. Evodevo (2019). 10(1).